| Date | Time | Description | Venue |
|---|---|---|---|
| Saturday, 13 February 2010 | 6:30PM | QR Reds - 28 v Waratahs - 30 | Suncorp Stadium |
| Friday, 19 February 2010 | 7:30PM | QR Reds - 41 v Canterbury Crusaders - 20 | Suncorp Stadium |
| Saturday, 27 February 2010 | 6:30PM | QR Reds - 18 v Auckland Blues - 27 | Ballymore |
| Friday, 5 March 2010 | 4:35PM | Chiefs - 18 v QR Reds - 23 | Waikato Stadium |
| Sunday, 14 March 2010 | 4:30PM | QR Reds - 50 v Western Force - 10 | Suncorp Stadium |
| Saturday, 27 March 2010 | 3:10AM | Cheetahs - 10 v QR Reds - 31 | Vodacom Park |
| Sunday, 4 April 2010 | 1:05AM | Sharks - 30 v QR Reds - 28 | Absa Stadium |
| Sunday, 11 April 2010 | 3:10AM | Lions - 26 v QR Reds - 41 | Coca-Cola Park |
| Saturday, 17 April 2010 | 7:30PM | QR Reds - 19 v Bulls - 12 | Suncorp Stadium |
| Friday, 23 April 2010 | 7:30PM | QR Reds - 16 v Stormers - 13 | Suncorp Stadium |
| Saturday, 1 May 2010 | 7:40PM | ACT Brumbies - 32 v QR Reds - 12 | Canberra Stadium |
| Friday, 7 May 2010 | 5:35PM | Hurricanes - 44 v QR Reds - 21 | Westpac Stadium |
| Saturday, 15 May 2010 | 7:30PM | QR Reds - 38 v Highlanders - 36 | Suncorp Stadium |
